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M. Stat. – 514
Physical Health and Human Growth Modeling
Full marks – 75
(Examination 60, Tutorial/Terminal 11.25, and Attendance 3.75)
Number of Lectures – Minimum 45
(Duration of Examination: 4 Hours)

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Aim of the Course
The aim of this course is to cover out the in depth knowledge on human growth process, body composition, body shape and size, different types of growth maturations, analysis of growth events, lung capacity, lung related other variables, pre-caution of growth failure, heart failure and its causes, finding risk factor of heart failure, different parametric and non-parametric growth model and higher dimensional growth model to understand and predict biological variables and adult stature.
Objectives of the Course
After completing this course, the students should
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understand all the features of human growth, and morphometric;
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apply longitudinal data to fit human growth model in two or higher dimensions; and
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understand the diseases and disorder of growth process;

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Learning Outcomes 
At the end of the course, the students will be able to
  » know how to develop growth chart;
  » know how to use statistics in Medical Science;
  »  know how to assess growth status;
  » diagnostic growth failure, heart failure and lung problems; and
  » predict final stature of a child, and so on.

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Course Contents
Morphometry: Basic concepts, stature, weight, BMI, vital capacity, strength, sitting-height, chest circumference, Bouchard’s index. Livi’s weight-height index. Body Mass Index (BMI), Rohrer’s body build index, index of morphological equilibrium. Grid method and auxogram.  Manouverier’s indexes of body build. Cormic index. Pirguet’s index of body build, Demeny’s vital index, Speh’s index, Bruugsch’s chest-stature index, Pignet’s coefficient of robusticity,
Craniometry and Osteometry: Planes of orientation, cranial landmarks, craniometric indices and cranial capacity. Osteometry, index of the body, foramen and Baudoin’s sexual index vertebral index and Cunningham’s index. Measurement of sacrum and long bones. Elliptical Fourier Analysis.
Growth and Maturation: Basic concepts, stages in child growth, early childhood, mid-childhood, late childhood, adolescence, prenatal and postnatal growth,  Skeletal maturation, sexual maturation, age at menarche, body composition and nutritional status, sequence of adolescent events.
Lung Capacity: Introduction, Vital Capacity and its measurement, Tidal Volume, Inspiratory Vital Capacity, Expiratory Vital Capacity, Total Lung Capacity,  Forced Expiratory Vital Capacity,  Forced Expiratory Volume, and their relationship
Growth Failure: Introduction, synonyms and keywords, Symptoms, Causes, Exam and test, Treatment.
Heart Failure: Concept, Relation between Heart Rate and Age, Classes of Heart Failure, Warning sign of Heart Failure, Risk of Heart Failure, Symptom & Diagnosis, Prevention & Treatment, Advanced Heart Failure,
Growth Model: Biological variables and its secular trends, Algometry Model, the Gompertz and logistic growth models, Jenss model, Count model, double logistic model, PB models, ICP model, Reed models, SSC model, JPPS model, JPA-1 and JPA-2 models, modified ICP model, BTT model and Kernel’s (non-parametric) model, Wavelet model, polynomial model, growth variations due to genetics and nutrition. Twin growth, heritability of growth.
Higher Dimensional Growth Model: Extension of BTT model, Extension of other growth models.

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Main Books:
1)
Alex F. Roche (1992). Growth Maturation and Body Composition: The Longitudinal Study 1029.1991, Cambridge University press.
2)
Beck, R.D., dueToit SHC and Thissen, D.(1994). AUXAL: Axiological  Analysis of Longitudinal Measurements of Human Stature, Chicago: SSI
3)
Shahin, M A, M. A Ali, ABM S. Ali (2013). An Extension of Generalized Triphasic Logistic Human Growth Model. J Biomet Biostat 4: 162. doi:10.4172/2155-6180.1000162
Books/Scientific Paper Recommended:
4)
Falkner, F. and Tanner J.M.(1978): Human Growth, vol.3: Neurobiology and Nutrition, Plenum Press, New York.
5)
Falkner, F. and Tanner, J.M.(1978): Human Growth, vol. I: Principles and Prenatal Growth, Plenum Press, New York and London.
6)
Falkner, F. and Tanner, J.M.(1978): Human Growth, vol.3: Neurobiology and Nutrition, Plenum Press, New York and London.
7)
Fleiss, J.L.(1981) : Statistical Methods for Rates and Proportions, Second Edition, John Wiley and Sons. N.Y.
8)
Hastic, T.,Tibshirani ,T., and Friedman,J.(2000): The Element of Statistical Learning: Data Mining Inference and Prediction, Springer, New York
9)
Johnston, F.E, Roche, A.F. and Susanne, C. (1980). Human Physical Growth and Maturation Methodologies and Factors, Plenum Press, New York.